PRP Hair Treatment
PRP therapy has proved its efficacy over last two decades as a medical treatment modality in the fields of oral surgery, neurosurgery, plastic and cosmetic surgery, sports medicine and orthopedics. With positive outcomes and success, it has been used as a medical adjunct therapy for skin and wound healing. But in the field of hair restoration, PRP hair therapy has not exceptionalized itself to challenge the status of FDA approved therapies like DHT Blockers and Minoxidil. Though PRP hair loss treatment yields good results in hair fall control and regrowth of new hairs.
In this procedure, a very small quantity of blood is drawn from a body, as though someone undergoes a blood test. Human blood consists of mesenchymal stem cells and autologous blood products which contains essential and special growth factor to stimulate regeneration and healing of tissues. The blood is spun in a centrifuge and PRP is separated and removed from the rest of the blood. The PRP is prepared by spinning down the blood cells to a high concentration. Platelets are concentrated to 3X the normal blood values. The concentration removes granulocytes which hinder tissue regeneration and wound healing. A local anesthesia is given to the nerves of the scalp to eliminate any feeling of pain. The highly concentrated Platelet Rich Plasma is then injected into the scalp. PRP contains special cells called platelets, inside the platelets there are many intracellular structures such as glycogen, lysosomes, and alpha granules, these granules contain clotting and growth factors which can help hair growth by stimulating the stem cells or other cells working around hair follicles when eventually released during the healing and repairing process. These concentrated platelet cells hastens the process of healing of the tissues and regeneration. The patient’s head is then washed and he may drive home without any assistant.
PRP specific cells which accelerate hair growth process include Platelet-Derived Growth Factor (PDGF), which promotes blood vessel growth, cell reproduction and skin formation, Transforming Growth Factor-Beta (TGF-b) which promotes growth of matrix between cell and bone metabolism, Vascular Endothelial Growth Factor (VEGF) which promotes blood vessels formation, Epidermal Growth Factor (EGF) which promotes cell growth, blood vessel formation and collagen formation, Fibroblast Growth Factor-2 (FGF-2) which promotes growth of specialized cells and blood vessel formation, and Insulin-Like Growth Factor – (IGF), a regulator of normal physiology in nearly every type of cell in the body.Though it is scientifically approved procedure, but there is always a factor of ambiguity regarding its effectiveness. This process is applicable for those patients who are not surgical candidates. And the outcomes may vary as per individual. No larger clinical study is made but current medical literature adopts a very optimistic attitude towards PRP.
PRP therapy is not meant for every individual victim of hair fall. Therapists exclude the patients with history of heavy smoking, drug and alcohol use, or patients who have undergone medical diagnosis such as platelet dysfunction syndromes, thrombocytopenias, hypofibrinogenaemia, hemodynamic instability, sepsis, acute and chronic Infections, chronic liver disease, anti-coagulation therapy, chronic skin diseases or cancer, metabolic and systemic disorders. PRP can help slow down hair loss and sometimes reverse thinning follicles. However it requires multiple treatments. And some evidences proved that once a patient stops the PRP treatments, he may step back to his natural pattern of hair loss.
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